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The reaction most likely to give intraepidermal vesicles is in fact an allergic contact dermatitis, but as I have already said drugs such as thiazide diuretics and calcium channel blockers can also cause spongiotic drug reactions. The eosinophils may infiltrate into the epidermis or they may be mainly perivascular in the dermis.
The reaction most likely to give intraepidermal vesicles is in fact an allergic contact dermatitis, but as I have already said drugs such as thiazide diuretics and calcium channel blockers can also cause spongiotic drug reactions. The eosinophils may infiltrate into the epidermis or they may be mainly perivascular in the dermis. 2020-12-15 · (B) Perivascular and interstitial dermatitis without epidermal changes. (C) Lymphocytes and eosinophils perivascular and numerous neutrophils interstitial. Figure 2 (A) Sharply demarcated purpuric erythema on the leg, a bulla Is seen in the uppermost part of the lesion.
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The small vessels are thick walled and are lined by plump endothelial cells. There are no atypical features. There is some perivascular fibroblastic proliferation with variable fibroplasia. The reaction most likely to give intraepidermal vesicles is in fact an allergic contact dermatitis, but as I have already said drugs such as thiazide diuretics and calcium channel blockers can also cause spongiotic drug reactions. The eosinophils may infiltrate into the epidermis or they may be mainly perivascular in the dermis.
2020-11-03 In one study, 46% of patients reported a positive family history. 7. Histologically, a perivascular lymphohistiocytic infiltrate is present in the superficial and sometimes deep dermis (Figs 8.29, 8.30 ).
2020-12-15
Authoritative facts from DermNet New Zealand. Both show spongiosis, superficial (and sometimes deep) perivascular lymphocytic infiltrates, and papillary dermal edema.
Interface dermatitis generally refers to a mild lichenoid-like reaction in the interface between epidermis and dermis. There is sparse scattered lymphocytic infiltration centred around the basal layer +/- vacuolar degeneration of the basal layer.
Pigment incontinence The pathologic features of urticarial dermatitis are nonspecific and include a normal stratum corneum, mild epidermal edema with minimal spongiosis, and a superficial to mid-dermal perivascular infiltrate of lymphocytes and eosinophils with occasional neutrophils (picture 1) [ 2 ]. A few basal apoptotic keratinocytes are sometimes present. Chapter 8 Superficial and deep perivascular inflammatory dermatoses Chronic superficial dermatitis 259 Toxic erythema 261 Erythema annulare centrifugum 261 Erythema gyratum repens 263 Lymphocytic infiltrate of the skin 264 Reticular erythematous mucinosis 265 Polymorphous light eruption 267 Tumid lupus erythematosus 269 Perniosis 270 Chilblain lupus erythematosus 272 Pigmented purpuric Pathological changes may arise in epidermis, dermis and/or subcutaneous tissue.
Juvenile spring eruption of the ears – Is likely a form of PMLE.
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Both also show vacuolar degeneration of the basal layer.
Signalment (JPC # 21474-17): Dog, breed unspecified HISTORY: This dog presented with pruritus and alopecia that was most severe in the skin of the lower back and base of tail.
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The pathologic features of urticarial dermatitis are nonspecific and include a normal stratum corneum, mild epidermal edema with minimal spongiosis, and a superficial to mid-dermal perivascular infiltrate of lymphocytes and eosinophils with occasional neutrophils (picture 1) [ 2 ]. A few basal apoptotic keratinocytes are sometimes present.
Polymorphic light eruption (PMLE) is a form of photosensitivity, which usually occurs in younger females.It is more common in patients who receive only intermittent sun exposure and typically consists of crops of papules, vesicles or plaques. Predominantly, a superficial perivascular lymphocytic infiltrate, extravasation of erythrocytes, and focal interface changes characterized DRESS cases. Less frequently, histopathology revealed the presence of necrotic keratinocytes; surprisingly, only in 2 cases the presence of rare dermal eosinophils was detected, even if all the patients had significant peripheral eosinophilia.